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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC4
All Species:
39.7
Human Site:
S772
Identified Species:
54.58
UniProt:
Q9NTJ3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTJ3
NP_001002800.1
1288
147182
S772
S
S
L
V
I
E
I
S
E
E
E
V
N
K
M
Chimpanzee
Pan troglodytes
XP_001157958
1288
147223
S772
S
S
L
V
I
E
I
S
E
E
E
V
N
K
M
Rhesus Macaque
Macaca mulatta
XP_001099428
1287
147121
S771
S
S
L
V
T
E
I
S
E
E
E
V
N
K
M
Dog
Lupus familis
XP_535848
1288
147094
S772
S
S
V
V
V
E
I
S
E
E
E
V
N
R
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG47
1286
146876
S770
S
S
V
I
D
E
I
S
V
E
E
V
N
K
M
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
T724
S
D
L
E
Q
T
K
T
R
H
L
A
L
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510551
1069
122201
Y607
S
L
L
E
Q
E
I
Y
L
K
G
Q
V
R
E
Chicken
Gallus gallus
NP_989849
1274
145838
S743
S
S
V
V
T
D
V
S
P
E
E
V
N
R
L
Frog
Xenopus laevis
P50532
1290
146971
S766
S
S
V
M
V
E
I
S
D
D
Q
L
Q
K
M
Zebra Danio
Brachydanio rerio
NP_775360
1289
145687
T771
S
S
F
C
A
D
V
T
Q
E
Q
L
D
K
M
Tiger Blowfish
Takifugu rubipres
NP_001027927
1326
150958
S767
S
I
A
A
S
Q
I
S
Q
A
E
L
D
S
M
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
L1085
T
Q
T
T
I
K
D
L
Q
E
R
L
E
I
T
Honey Bee
Apis mellifera
XP_396862
1282
148175
S709
Q
I
L
K
N
E
I
S
S
I
D
I
E
I
L
Nematode Worm
Caenorhab. elegans
Q20060
1549
176553
A778
L
T
D
K
N
K
M
A
K
Q
V
T
P
E
D
Sea Urchin
Strong. purpuratus
XP_797583
1289
146235
T771
C
T
I
V
S
D
V
T
P
Q
V
V
A
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
G715
G
T
S
I
R
A
T
G
V
S
G
E
A
V
A
Baker's Yeast
Sacchar. cerevisiae
Q12267
1418
162171
K842
L
G
T
N
Q
S
D
K
V
D
D
Y
T
P
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
94
N.A.
89.5
24
N.A.
67.8
75.3
76.9
67.9
66.7
20.1
45.9
29.9
48.1
Protein Similarity:
100
99.6
98.9
96.5
N.A.
94.8
47.5
N.A.
75
86.3
87.5
83.5
81.2
40.2
63.9
47.5
65.4
P-Site Identity:
100
100
93.3
80
N.A.
73.3
13.3
N.A.
26.6
53.3
46.6
33.3
33.3
13.3
26.6
0
20
P-Site Similarity:
100
100
93.3
100
N.A.
86.6
26.6
N.A.
40
86.6
93.3
80
60
40
46.6
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.3
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
55.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
6
6
6
0
6
0
6
0
6
12
6
6
% A
% Cys:
6
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
6
0
6
18
12
0
6
12
12
0
12
0
6
% D
% Glu:
0
0
0
12
0
48
0
0
24
48
42
6
12
6
12
% E
% Phe:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
6
6
0
0
0
0
0
6
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% H
% Ile:
0
12
6
12
18
0
53
0
0
6
0
6
0
12
0
% I
% Lys:
0
0
0
12
0
12
6
6
6
6
0
0
0
36
0
% K
% Leu:
12
6
36
0
0
0
0
6
6
0
6
24
6
0
18
% L
% Met:
0
0
0
6
0
0
6
0
0
0
0
0
0
0
53
% M
% Asn:
0
0
0
6
12
0
0
0
0
0
0
0
36
6
0
% N
% Pro:
0
0
0
0
0
0
0
0
12
0
0
0
6
6
0
% P
% Gln:
6
6
0
0
18
6
0
0
18
12
12
6
6
0
0
% Q
% Arg:
0
0
0
0
6
0
0
0
6
0
6
0
0
18
0
% R
% Ser:
65
48
6
0
12
6
0
53
6
6
0
0
0
6
0
% S
% Thr:
6
18
12
6
12
6
6
18
0
0
0
6
6
0
6
% T
% Val:
0
0
24
36
12
0
18
0
18
0
12
42
6
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
6
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _